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1H spectroscopy in stroke
Authors:I. Marshall  R. J. Sellar
Affiliation:(1) Department of Medical Physics, University of Edinburgh, EH4 2XU Edinburgh, UK;(2) Department of Clinical Neurosciences, University of Edinburgh, EH4 2XU Edinburgh, UK;(3) Department of Medical Physics, Western General Hospital, EH4 2XU Edinburgh, UK
Abstract:We used proton spectroscopy to compare metabolite levels in infarcted brain tissue with the levels in corresponding normal white matter. In a preliminary study of six patients, the ratios (mean ± standard deviation) were 0.72±0.25 (p=0.04) for choline, 0.41±0.24 (p=0.002) for creatine, and 0.21±0.22 (p<0.001) forN-acetylaspartate.
Keywords:proton spectroscopy  stroke  ischaemia  infarct  brain metabolites
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