Comparison of two Varieties of Microcrystalline Cellulose as Filler-Binders II. Hydrochlorothiazide Tablets |
| |
| Authors: | M. Landí n M. P. Gonz lez C. Souto A. Concheiro J. L. G mez-Amoza R. Martí nez-Pacheco |
| |
| Affiliation: | a Departamento de Farmacologia, Farmacia Y Tecnologia Farmaceutica, Facultad de Farmacia. Santiago de Compostela, (Spain) |
| |
| Abstract: | In tests of direct-compression hydrochlorothiazide tablets prepared with either of two varieties of microcrystalline cellulose (Avicel PH 101 and Avicel PH 102), PH 102 tablets had better mechanical properties (owing to lower compressibility of mixtures and greater Interparticle bonding), while PH 101 tablets released the active principle faster. These differences are related to observed differences In tablet micropore structure. |
| |
| Keywords: | |
| 本文献已被 InformaWorld 等数据库收录！ |
