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Analysis of cellular phenotype during in vitro immunization of murine splenocytes for generating antigen-specific immunoglobulin |
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| Authors: | Takashi Inagaki Tatsunari Yoshimi Satoshi Kobayashi Masahiro Kawahara Teruyuki Nagamune |
| Affiliation: | 1 Innovative Antibody Engineering Laboratory, Advance Co. Ltd., 5-7 Kobunacho, Chuo-ku, Tokyo 103-8354, Japan;2 Department of Bioengineering, Graduate School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan;3 Department of Chemistry and Biotechnology, School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan |
| Abstract: | |
| Keywords: | In vitro immunization Activation-induced cytidine deaminase Germinal center Somatic hypermutation T cell dependent stimuli |
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