| 醇腈酶催化合成手性氰醇的研究进展 |
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| 引用本文： | 褚朝森,韩世清,韦萍.醇腈酶催化合成手性氰醇的研究进展[J].化工生产与技术,2007,14(6):55-59. |
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| 作者姓名： | 褚朝森 韩世清 韦萍 |
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| 作者单位： | 南京工业大学,南京,210009;南京工业大学,南京,210009;南京工业大学,南京,210009 |
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| 摘 要： | 概括了不同来源醇腈酶的结构及其催化合成手性氰醇的立体构型.举例证实醇腈酶能够催化除天然底物外的多种底物的羟氰化反应,有广泛的应用价值,并对醇腈酶在手性药物合成中的应用作了介绍.
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| 关 键 词： | 醇腈酶 手性氰醇 不对称合成 |
| 文章编号： | 1006-6829（2007）06-0055-05 |
| 收稿时间： | 2007-10-19 |
| 修稿时间： | 2007-11-08 |
Research Progresses on the Synthesis of Chiral Cyanohydrins Catalyzed by Oxynitrilases |
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| Chu Chaosen,Han Shiqing,Wei Ping.Research Progresses on the Synthesis of Chiral Cyanohydrins Catalyzed by Oxynitrilases[J].Chemical Production and Technology,2007,14(6):55-59. |
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| Authors: | Chu Chaosen Han Shiqing Wei Ping |
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| Abstract: | Structures and spatial configurations of the corresponding cyanohydrins catalyzed by oxynitrilases with different source were summarized. Some examples were given to confirm that many non-nature substrates could be catalyzed by oxynitrilases, which are widely applied. Its applications in the synthesis of chiral pharmaceuticals is introduced. |
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| Keywords: | oxynitrilases chiral cyanohydrins asymmetric synthesis |
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