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Preparation and Properties of Bioactive Composite Based on Bioactive Glass and Poly-L-Lactide |
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| Authors: | Zhou Zhihua Ruan Jianming Zhou Zhongcheng Zou Jianpeng Chen Lianglong |
| Affiliation: | 1. College of Chemistry and Chemical Engineering, Hunan University of Science and Technology , Xiangtan, China zhou7381@sohu.com;3. State Key Laboratory for Powder Metallurgy, Central-South University , Changsha, China;4. Department of Orthopedics , Second Xiangya Hospital, Central South University , Changsha, China |
| Abstract: | Bioactive and bioresorbable composite was fabricated based on poly-L-lactide (PLLA) and bioactive glass (average particle size: 4.24 µm) by the combination of solvent evaporation technique and hot pressing. Bioactive glass granules are distributed homogeneously in the composite. With the increasing of the amount of bioactive glass, the bending strength and shearing strength of composite decrease while the bending modulus increases. PLLA/bioactive glass composites present a typical morphology of brittle failure with a smooth fracture surface. The biocompatibility test shows that the bioactive glass existing in the composite facilitates both adhesion and proliferation of rat fibroblast on the PLLA/bioactive glass composite film. |
| Keywords: | Bioactive glass Biocompatibility Composite Mechanical properties Poly-L-lactide |