羟基磷灰石负载氯化锌催化剂用于苯甲醚酰化反应

 以羟基磷灰石(HAP)为载体，采用水热法制备了羟基磷灰石负载 ZnCl₂催化剂(ZnCl₂/HAP)。采用 FT-IR、XRD、BET 等手段对载体和催化剂进行了表征，并将制备的 ZnCl₂/HAP 应用于苯甲醚与烷基酰氯的酰基化反应，考察了反应条件对酰基化反应的影响和 ZnCl₂/HAP 的稳定性。结果表明，当催化剂活化温度为150℃、ZnCl₂负载量为1 mmol/g、反应时间5 h、ZnCl₂/HAP 与酰氯的摩尔比为1∶25时，ZnCl₂/HAP 对该酰基化反应的催化活性最高，对烷酰基苯甲醚的产率可达78%~88%。ZnCl₂/HAP重复使用5次仍具有较高的催化活性。

Hydroxyapatite Supported ZnCl2 Catalyst for the Acylation of Anisole

The hydroxyapatite(HAP) supported zinc chloride catalyst(ZnCl₂/HAP) for Friedel-Crafts acylation of anisole with acyl chloride was prepared by the hydrothermal method. HAP and ZnCl₂/HAP were characterized by means of FT-IR, XRD and BET. The effects of reaction conditions and stability of ZnCl₂/HAP for the acylation reaction were studied. The results showed that the suitable calcination temperature of catalyst, ZnCl₂ loading, reaction time and the molar ratio of catalyst to acyl chloride were 150℃, 1 mmol/g, 5 h, 1∶25, respectively. Under the optimal conditions, the yield of 4-acyl anisole was 78%-88%. Moreover, the catalyst ZnCl₂/HAP still has higher activity within reuse of five times.