4-甲基咪唑的合成 |
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引用本文: | 黄永明,梁强,陈吉伟,章道道.4-甲基咪唑的合成[J].精细化工,1994(4). |
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作者姓名: | 黄永明 梁强 陈吉伟 章道道 |
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作者单位: | 复旦大学化学系 |
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摘 要: | 报道了药物中间体4-甲基咪唑的合成方法,研究了以丙酮醛、甲醛及氨水为原料的合成路线,对文献方法作了改进,并用DSC、IR、NMR等方法对产物进行了鉴定。
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SYNTHESIS OF 4-METHYL-IMIDAZOLE |
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Abstract: | Abstract An improved synthetic method of 4-methyl-imidazole,an intermediate of me-dicines,is reported.After intensive study ofthe approach beginning with pyruvic alde-hvde,formaldehyde and ammonia water,au-thors improved the approach reported beforeand identified the product by methods such asDSC,IR and NMR. |
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