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Star polymers for gene delivery
Authors:Theoni K Georgiou
Abstract:Star polymers are hyperbranched polymers with fascinating properties and exhibiting self‐assembly behaviour that have recently attracted a lot of interest in the field of gene delivery. This perspective aims to summarize the latest studies of star polymers as gene delivery vectors. Specifically, the aim is to identify and discuss the main synthetic methodologies that are used to fabricate star polymers and which structural characteristics affect their ability to be used as gene delivery agents. © 2014 Society of Chemical Industry
Keywords:polymers  star polymers  in‐out star  arm‐first star  core‐first star  hyperbranched polymers  nanomedicine  gene therapy  gene delivery  DNA delivery  siRNA delivery  molecular weight effect  architecture effect
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