| Abstract: | Investigations performed during prolonged microgravity were aimed at determination of phenomenology of the microgravity effects, and collection of data that would permit analysis of the micro-g specific homeostasis. As was stated, long-term microgravity alters the level of functioning of the main body systems, and a number of parameters of human metabolism and internal medium. It also instigates restructuring of some tissues and organs (primarily the musculoskeletal apparatus), brings along another level of energy and plastic (protein) metabolism, enhances the catabolic processes, and modifies the neuroendocrine regulation. In microgravity, the balance of functional loads on various body systems changes affecting rearrangement of the homeostasis regulation. The paper details the functional and morphological changes arising during long stay in microgravity and mechanisms culminating in a novel homeostasis in microgravity. |
