| 叶绿素对ob/ob肥胖小鼠炎症指标的影响 |
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| 引用本文： | 王潇,欧雅文,李媛媛,张燕,.叶绿素对ob/ob肥胖小鼠炎症指标的影响[J].中国食品学报,2021,21(1):90-95. |
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| 作者姓名： | 王潇 欧雅文 李媛媛 张燕 |
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| 作者单位： | 中国农业大学食品科学与营养工程学院国家果蔬加工工程技术研究中心; |
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| 基金项目： | 国家自然科学基金面上项目（31571844） |
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| 摘 要： | 研究叶绿素对肥胖小鼠相关炎症指标的影响,以探究叶绿素发挥的生物活性作用。在高脂饲料喂养条件下,给ob/ob肥胖小鼠灌胃叶绿素,测定其血糖、体重、摄食量等指标;采用酶联免疫吸附试验测定血清炎症因子(TNF-α、IL-6、LEP)和血清内毒素(ET)水平变化。结果表明,叶绿素可显著降低ob/ob肥胖小鼠体内促炎因子以及ET水平(P<0.05),促进脂联素水平的升高,从而调节肥胖相关炎症指标。
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| 关 键 词： | 叶绿素 肥胖 炎症 |
Effect of Chlorophyll Supplementation on Inflammation Factors of ob/ob Obese Mice |
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| Wang Xiao,Ou Yawen,Li Yuanyuan,Zhang Yan.Effect of Chlorophyll Supplementation on Inflammation Factors of ob/ob Obese Mice[J].Journal of Chinese Institute of Food Science and Technology,2021,21(1):90-95. |
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| Authors: | Wang Xiao Ou Yawen Li Yuanyuan Zhang Yan |
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| Affiliation: | (College of Food Science and Nutritional Engineering,China Agricultural University,National Engineering Research Centre for Fruit and Vegetable Processing,Beijing 100083) |
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| Abstract: | To investigate the effects of chlorophyll on related inflammatory markers in obese mice,so as to explore the biological activity of chlorophyll.Chlorophyll was administered to the obese mice to measure blood sugar,body weight,food intake and other indicators while feeding the high-fat feed.Serum inflammatory factors(TNF-α,IL-6,LEP)and serum endotoxin(ET)were measured by ELISA to analyze the effect of chlorophyll on inflammatory factors in obese mice.The results showed that chlorophyll can significantly reduce inflammatory factors and ET level(P<0.05),and promote the increase of adiponectin level,which has effects on obesity-related inflammation. |
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| Keywords: | chlorophyll obesity inflammation |
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