纯钛表面立方介孔SiO2薄膜诱导沉积碳磷灰石层

采用浸渍-提拉法在预处理纯钛表面制备立方介孔SiO₂薄膜, 通过评价体外诱导类骨碳磷灰石层形成能力研究其生物活性。利用小角X射线衍射、傅立叶变换红外光谱、N₂吸附、电镜和能谱等测试技术对模板剂去除前后、模拟体液浸泡前后介孔薄膜结构、组成与形貌进行了研究; 利用固体表面Zeta电位仪研究薄膜表面荷电性质。结果表明, 介孔薄膜具有三维立方介孔结构, 在模拟体液(1.5SBF)中浸泡14 d即能诱导碳磷灰石层在其表面沉积, 显示出良好的生物活性。介孔薄膜独特的孔道结构以及孔表面Si-OH在体液中呈负电性对其生物活性起关键作用。

Cubic Mesoporous Silica Thin Films Coated on Titanium to Induce Carbonated Hydroxyapatite Deposition

Cubic mesoporous silica thin films were synthesized on pure titanium by dip-coating method and then their bioactivity were evaluated through the induced deposition of bone-like carbonated hydroxyapatite (CHA) layer in vitro. The composition, microstructure and morphology of the films were characterized by small-angel X-ray diffraction, Fourier transform infrared spectrum, nitrogen adsorption, electron microscopes and energy dispersive spectroscopy, etc. The surface Zeta potential of the films was investigated by electrokinetic analyzer for solid surface analysis. The results reveal that the films have three-dimensional cubic mesostructure. The mesoporous silica films are covered with a thin CHA layer after being soaked in a simulated body fluid (1.5 SBF) for 14 d, indicating its good bioactivity. The unique mesostructure and the presence of abundant electronegative silanol groups in physiological solution may be responsible for the bioactivity.