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31P magnetic resonance spectroscopy of the liver in an infant with galactosaemia |
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| Authors: | J P Smyth P L Hope R M Dixon R Ouwerkerk B Rajagopalan G K Radda |
| Affiliation: | (1) Department of Paediatrics, John Raddiffe Hospital, Oxford, UK;(2) Special Care Nursery, John Radcliffe Maternity Hospital, Headington, OX3 9DU Oxford, UK;(3) Medical Research Council Biochemical and Clinical Magnetic Resonance Unit, John Radcliffe Hospital, Oxford, UK |
| Abstract: | Sequential studies of the liver of an infant with galactosaemia were made by phosphorus magnetic resonance spectroscopy (31P MRS). A peak attributable to galactose 1-phosphate (gal 1-P) was seen in early liver spectra. This peak diminished during dietary therapy in the early months of life, corresponding to a falling level of gal 1-P in red blood cells. |
| Keywords: | spectroscopy galactosaemia liver infant galactose 1-phosphate |
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