| 对乙酰氨基苯酚的合成进展 |
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| 引用本文： | 赵海,王纪康. 对乙酰氨基苯酚的合成进展[J]. 化工技术与开发, 2004, 33(1): 17-21 |
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| 作者姓名： | 赵海 王纪康 |
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| 作者单位： | 浙江工业大学药学院,浙江,杭州,310014;浙江工业大学药学院,浙江,杭州,310014 |
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| 摘 要： | 综述了近年来国内外有关对乙酰氨基酚及其中间体对氨基酚的合成方法，通过对其合成方法(如二步法、一步法，重排法和生化法等)的比较，认为一步法合成将是对乙酰氨基酚生产的发展方向。
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| 关 键 词： | 对乙酰氨基苯酚 扑热息痛 对氨基苯酚 |
| 文章编号： | 1671-9905(2004)01-0017-05 |
| 修稿时间： | 2003-12-01 |
Development of Synthesis of Acetaminophen |
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| ZHAO Hai,WANG Ji-kang. Development of Synthesis of Acetaminophen[J]. Technology & Development of Chemical Industry, 2004, 33(1): 17-21 |
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| Authors: | ZHAO Hai WANG Ji-kang |
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| Abstract: | The preparation methods of acetaminophen and its intermediate p-aminophenol were reviewed. Acetaminophen can be prepared by one-step,two-step, or rearrangement and biochemical method. It was pointed out that one-step method would be the best way for producing acetaminophen by compared one-step method with other methods. |
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| Keywords: | acetaminophen paracetamol p-aminophenol |
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