Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials |
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| Affiliation: | 1. Institute of Biotechnology, National Taipei University of Technology, Taipei, Taiwan;2. Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan;3. Graduate Institute of Manufacturing Technology, National Taipei University of Technology, Taipei, Taiwan;1. Production Engineering Department, Guru Nanak Dev Engineering College, Ludhiana-141006, India;2. Mechanical Engineering Department, Punjabi University, Patiala-147002, India;1. State Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong 250100, China;2. Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong 250100, China;3. Institute for Advanced Interdisciplinary Research (IAIR), University of Jinan, Jinan 250022, China;4. School of Physical Science and Technology, Shanghai Tech University, Shanghai 201210, China;5. Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, Shandong 250100, China |
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| Abstract: | Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications. |
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