| Ca2+和Pb2+与双层类脂膜相互作用的研究 |
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| 引用本文： | 张彦莉,沈含熙.Ca2+和Pb2+与双层类脂膜相互作用的研究[J].化学传感器,2001,21(1):34-41. |
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| 作者姓名： | 张彦莉 沈含熙 |
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| 作者单位： | 1. 南开大学化学系,天津,300071;军事医学科学院卫生学环境医学研究所,天津,300050
2. 南开大学化学系,天津,300071 |
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| 基金项目： | 国家自然科学基金(No.29675009)资助项目 |
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| 摘 要： | 用电化学方法研究了卵磷脂和氧化胆固醇构成的双层类脂膜与 Ca~(2+)和 Pb~(2+)的相互作用。结果发现:双层类脂膜与含 Ca~(2+)或 Pb~(2+)的溶液接触15分钟后,产生较稳定的膜电位信号并与溶液中 Ca~(2+),Pb~(2+)浓度相关。其作用机制主要是源于静电作用与合作效应,同时,对三种不同存在状态的双层类脂膜的通透性进行了验证,对某些干扰离子和 pH 值的影响进行了研究。
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| 关 键 词： | 双层类脂膜 Ca~(2+)和Pb~(2+) 相互作用 电化学研究 |
The study on calcium and lead ions interacting with bilayer lipid membranes |
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| Zhang Yan-li,Shen Han-xi.The study on calcium and lead ions interacting with bilayer lipid membranes[J].Chemical Sensors,2001,21(1):34-41. |
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| Authors: | Zhang Yan-li Shen Han-xi |
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| Abstract: | The present paper studied the interaction of Ca~(2+) and Pb~(2+) with bilayer lipid membranes (BLMs).The results showed that the stable membrane potential E_(mf) appeared after 15 minutes when Ca~(2+) or Pb~(2+) ions were added into the electrolyte.The values of E_(mf) were related to the concentration of Ca~(2+) or Pb~(2+) in bulk solution.The mechanism of inter- action may be result from electrostatic interaction and cooperation effect.Effects of coexis- tent metal ions and pH were investigated in details. |
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| Keywords: | bilayer lipid membranes Ca~(2+) and Pb~(2+) interact electrochemical research |
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