超声造影与对比增强CT诊断肝细胞癌的比较研究

目的采用超声造影(CEUS)新技术诊断肝细胞性肝癌(HCC),与对比增强CT(CECT)比较其增强表现,评估CEUS的临床应用价值。方法98个HCC病灶接受了CEUS和CECT检查。CEUS造影剂为声诺维,对比脉冲序列(CPS)成像技术。CECT造影剂为优维显,常规双期增强扫描。结果98个(100%)病灶在CEUS和CECT动脉期均显示增强,表现为高增强分别为98个(100%)和94个(95.9%,P=0.121),CECT4个(4.1%)病灶表现为等增强。在门脉期,CEUS和CECT显示病灶消退至低增强分别为82个(83.7%)和83个(84.7%),P=0.845。CEUS和CECT显示肿瘤周边薄环状增强的病灶数目分别为30个(30.6%)和31个(31.6%,P=0.877),显示瘤内血管的病灶数目分别为94个(95.9%)和36个(36.7%,P=0.000)。结论HCC的CEUS增强表现与CECT一致,为临床提供了一种简便易行的HCC定性诊断手段。

A Comparison Study of Contrast-enhanced Ultrasonography with Contrast-enhanced Computed Tomography in Enhancement Pattern of Hepatocellular Carcinoma

Objective To compare contrast-enhanced ultrasound (CEUS) with contrast-enhanced computed tomography (CECT) in enhancement pattern of hepatocellular carcinoma (HCC).Methods Ninety-two HCC patients with 98 lesions underwent examination of CEUS and CECT.CEUS was performed with SonoVue and contrast pulse sequencing(CPS).CECT was performed with Ultravist and a standard biphasic helical CT scanning procedure.Results All of the 98 lesions (100%) showed enhancement on CEUS and CECT in arterial phase.The number of the lesions with hyper-enhancing on CEUS and CECT was 98(100%) and 94(95.9%),respectively (P=0.121).Four (4.1%) lesions showed iso-enhancing in arterial phase on CECT.In portal phase,the number of the lesions with hypo-enhancing on CEUS and CECT was 82 (83.7%) and 83(84.7%),respectively (P=0.845).Peripheral thin-rim-like enhancement was exhibited in 30 lesions (30.6%) on CEUS and 31 (31.6%) on CECT (P=0.877).With regard to intratumoral vessels,the visualization was found in 94 (95.9%) lesions on CEUS and 36(36.7%) on CECT (P=0.000).Conclusions The enhancement pattern of HCC on CEUS was consistent with that on CECT,whereas CEUS has the advantages of easy performance,real-time scanning and readily available.