四氮杂杯[2]芳烃[2]三嗪的合成及其叠氮化研究

研究了四氮杂杯2]芳烃2]三嗪的合成及其叠氮化。以三聚氯氰和间苯二胺(摩尔比>2∶1)为原料,碳酸钾为缚酸剂,四氢呋喃为溶剂,在冰浴条件下合成中间体N,N’-二(4,6-二氯-1,3,5-均三嗪-2-基)-1,3-苯二胺,产率为85.8%;该中间体和间苯二胺(摩尔比为1∶1)丙酮为溶剂,在室温条件下反应,生成四氮杂杯2]芳烃2]三嗪,产率为45.5%;四氮杂杯2]芳烃2]三嗪和叠氮钠在40~50℃条件下反应生成四氮杂杯2]-1,5-芳烃2]-2-叠氮基-1,3,5-三嗪产率为90.0%。产物通过元素分析、红外光谱和氢谱的表征,其结构得到了确定。

Study on synthesis of tetraazacalix[2]arene[2]triazine and its azidotion

This paper studied the synthesis of tetraazacalixarene2]triazine and its azidotion.In ice temperature,using cyanuric chloride and m-phenylenediamine(the mole ratio >2 ∶1) as materials,potassium carbonate was taken as neutralisatal reagents,THF as solvent,synthesized the intermediate,the yield may up to 85.8%;synthesized tetraazacalixarene2]triazine by the intermediate and m-phenylenediamine(the mole ratio 1 ∶1),in room temperature,acetone as solvent,the yield is 45.5%;tetraazacalix2]arene2]triazine and its azidotion was prepared in 40~50 ℃ synthesized its azidotion by tetraazacalix2]arene2]triazine and sodium azide,the yield is 90.0%.The product was characterized by IR,element analysis and 1H NMR and its structure was also determined.