Investigation on infrared laser desorption of solid matrix using scanning electron microscope and fast photography |
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Authors: | Xing Fan Shou‐Ze Wang Ai‐Li Zheng Xian‐Yong Wei Yun‐Peng Zhao Zhi‐Min Zong Wei Zhao |
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Affiliation: | 1. School of Chemical Engineering, China University of Mining and Technology, , Xuzhou, 221116 Jiangsu, People's Republic of China;2. Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China Institute of Technology, , Nanchang, Jiangxi Province, 330013 People's Republic of China |
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Abstract: | Infrared light from a pulsed optical parametric oscillator laser system was used to irradiate succinic acid (SA), a usual solid matrix used in matrix‐assisted laser desorption ionization, under vacuum. Ablated SA particles were trapped using a silica plate mounted 3.0 mm above and parallel to the sample surface. The morphology and particle size of ablated particles at different laser fluences were investigated using a scanning electron microscope (SEM). The dynamics of plume propagation for SA desorption process was studied with fast photography at atmospheric pressure. Plume expanding at 1.12 J/cm2 laser fluence was recorded using a high‐speed CMOS camera and corresponding propagation distance was measured. The solid matrix desorption was driven by phase explosion according to plume model fitting, which was consistent with the results of SEM. Microsc. Res. Tech. 76:744–750, 2013. © 2013 Wiley Periodicals, Inc. |
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Keywords: | scanning electron microscope fast photography laser desorption optical parametric oscillator |
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