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Hepatic arterial infusion chemotherapy (HAI) for advanced hepatocellular carcinoma inefficacious with transcatheter arterial embolization (TAE) |
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| Authors: | W Takayama T Asano S Kobayashi S Nakagouri T Kenmochi S Okazumi A Takeda T Fukunaga K Iwasaki K Shutou H Matsuzaki H Aoyama K Shinotou T Kouno K Isono |
| Affiliation: | Second Dept. of Surgery, Chiba University School of Medicine. |
| Abstract: | For 6 patients with advanced hepatocellular carcinoma (HCC) in whom TAE was inefficacious, we tried hepatic arterial infusion chemotherapy. 5-FU 500 mg/day + CDDP 10 mg/day was administered during 5 days. The AFP level was decreased for 4 patients, and 2 patients showed a partial response in CT image. These 2 patients have been alive over 22 and 18 months, respectively. These results suggest that 5-FU + CDDP HAI might be a useful treatment of HCC inefficacious with TAE. |
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