抗溶剂气体重结晶制备聚碳硅烷纳米微粒的溶剂选择

将理论计算和实验相结合来选择聚碳硅烷(PCS)抗溶剂气体重结晶过程的溶剂。首先，理论计算了聚碳硅烷的溶度参数，并根据极性相似相溶原理筛选出几种待选溶剂；然后，实验比较CO2对待选溶剂的体积膨胀，待选溶剂与CO2、PCS的溶解情况和PCS在待选溶剂中的析晶率。研究结果表明：在3种待选溶剂四氢呋喃、对二甲苯和环己烷中，以四氢呋喃的性能最佳。以四氢呋喃作溶剂，采用抗溶剂气体重结晶工艺制备出的PCS纳米微粒平均粒径为2．2nm，颗粒粒径分布较为集中。

Selection of the Solvent in PCS Nanoparticle Preparation Process by Gas Antisolvent Recrystallization

Based on the combination of theoretical calculation and experimental measure- ment, the study on the solvent in PCS nanoparticle preparation process by gas antisol- vent recrystallization was carried out. The PCS's solvent parameter is calculated with the theoretical method, and some solvents such as cyclohexane, p--dimethyl benzene and tetrahydropyrane, are adopted according to the calculated result. The volume expansion of solvent with the solved CO_2, the solubilities of solvent in CO_2, and the PCS in solvent are measured for the adopted solvents. The experimental results indicate that the per- formance of tetrahydropyrane is the best among the three solvents, and the PCS nano- particle with a average size of 2. 2 nm is prepared using the tetrahydropyrane as solvent.