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Ti-3Zr-2Sn-3Mo-25Nb合金表面活性微弧氧化膜的制备及其骨诱导性(英文)
引用本文:余森,于振涛,韩建业,麻西群,Matthew S.DARGUSCH. Ti-3Zr-2Sn-3Mo-25Nb合金表面活性微弧氧化膜的制备及其骨诱导性(英文)[J]. 中国有色金属学会会刊, 2011, 0(3): 573-580
作者姓名:余森  于振涛  韩建业  麻西群  Matthew S.DARGUSCH
作者单位:西北有色金属研究院;CAST;Cooperative;Research;Centre;School;Mechanical;Mining;Engineering;University;Queensland;
基金项目:Project (2005CB623904) supported by the National Basic Research Program of China;Project (30770586) supported by the National Natural Science Foundation of China;Project (31011120049) supported by the Australia-China special fund, International Science Linkages Program co-supported by the Department of Innovation, Industry, Science and Research of Australia, and the Ministry of Science and Technology and National Science Foundation of China;Project (2010ZDKG-96) supported by the major Subject of “13115” Programs of Shaan’xi Province, China
摘    要:通过微弧氧化法在新型医用近β钛合金Ti-3Zr-2Sn-3Mo-25Nb表面制备一层含Ca、P多孔薄膜,再将其在胺基化溶液中活化处理以在薄膜表面引入NH-2。借助XRD、SEM和EDS研究该多孔复合薄膜的组成和表面形貌,并通过模拟体液浸泡实验、体外细胞培养实验和动物体内植入实验研究经上述表面改性处理后的Ti-3Zr-2Sn-3Mo-25Nb合金的骨诱导活性。结果表明:该薄膜主要由金红石型TiO2和锐钛矿型TiO2组成,是一种含有Ca、P的陶瓷混合物;薄膜在模拟体液中具有很好的生物活性,成骨细胞能够很好地在薄膜上分化、生长;表面覆膜处理的Ti-3Zr-2Sn-3Mo-25Nb合金的体内骨诱导活性优于未处理的Ti-3Zr-2Sn-3Mo-25Nb合金的。

关 键 词:β钛合金  Ti-3Zr-2Sn-3Mo-25Nb合金  骨诱导性  微弧氧化  表面改性

Preparation and osteoinduction of active micro-arc oxidation films on Ti-3Zr-2Sn-3Mo-25Nb alloy
YU Sen,YU Zhen-tao,Gui WANG,HAN Jian-ye,MA Xi-qun,Matthew S. DARGUSCH . Northwest Institute for Nonferrous Metal Research,Xi'an ,China,. CAST Cooperative Research Centre,School of Mechanical , Mining Engineering,The University of Queensl,Brisbane QLD ,Australia. Preparation and osteoinduction of active micro-arc oxidation films on Ti-3Zr-2Sn-3Mo-25Nb alloy[J]. Transactions of Nonferrous Metals Society of China, 2011, 0(3): 573-580
Authors:YU Sen  YU Zhen-tao  Gui WANG  HAN Jian-ye  MA Xi-qun  Matthew S. DARGUSCH . Northwest Institute for Nonferrous Metal Research  Xi'an   China  . CAST Cooperative Research Centre  School of Mechanical    Mining Engineering  The University of Queensl  Brisbane QLD   Australia
Affiliation:YU Sen1,2,YU Zhen-tao1,Gui WANG2,HAN Jian-ye1,MA Xi-qun1,Matthew S. DARGUSCH2 1. Northwest Institute for Nonferrous Metal Research,Xi'an 710016,China,2. CAST Cooperative Research Centre,School of Mechanical and Mining Engineering,The University of Queensland,Brisbane QLD 4072,Australia
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