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一种复合型抗光老化面霜的制备
引用本文:潘筱婕,申琳靖,张立秋,蒋硕,许雲,卢家乐,施溯筠.一种复合型抗光老化面霜的制备[J].延边大学理工学报,2022,0(1):76-81.
作者姓名:潘筱婕  申琳靖  张立秋  蒋硕  许雲  卢家乐  施溯筠
作者单位:(延边大学 药学院, 吉林 延吉 133002)
摘    要:针对紫外光易造成人体皮肤老化的问题,以金黄洋甘菊提取液和乳木果油为主要原料制备了一款新的复合型抗光老化面霜.采用DPPH法对金黄洋甘菊提取液进行了体外抗氧化活性测定;采用评分法以单因素试验和正交试验对面霜进行理化检测评价,并对基质配方进行了优化;通过斑贴试验测试面霜的安全性,并用智能皮肤分析仪测试面霜的试用效果.试验结果表明:当面霜基质中添加质量浓度为8.0 mg/mL的金黄洋甘菊提取液时,其对DPPH自由基的清除率达到最大;在基质中添加质量分数为7.0%的环五聚二甲基硅氧烷、1.0%的PEG-60、 13.3%的甘油时,面霜的综合效果最佳;面霜的耐热、耐寒、安全性等指标符合化妆品规范标准,且具良好的抗氧化性能.因此,该复合型抗光老化面霜具有很好的开发利用价值.

关 键 词:金黄洋甘菊  乳木果油  面霜  抗氧化

Preparation of a compound anti-photoaging face cream
PAN Xiaojie,SHEN Linjing,ZHANG Liqiu,JIANG Shuo,XU Yun,LU Jiale,SHI Suyun.Preparation of a compound anti-photoaging face cream[J].Journal of Yanbian University (Natural Science),2022,0(1):76-81.
Authors:PAN Xiaojie  SHEN Linjing  ZHANG Liqiu  JIANG Shuo  XU Yun  LU Jiale  SHI Suyun
Affiliation:(College of Pharmacy, Yanbian University, Yanji 133002, China)
Abstract:Aiming at the problem that ultraviolet light easily causes aging of human skin, a new compound anti-photoaging cream was prepared with chrysanthellum indicum extract and shea butter as main raw materials.The antioxidant activity of chrysanthellum indicum extract in vitro was determined by DPPH method; The single fator test and orthogonal test were used to evaluate the physical and chemical properties of the creamand the matrix formula was optimized.The safety of the cream was tested by patch test, and the trial effect of the cream was tested by the intelligent skin analyzer.The results showed that the scavenging rate of DPPH free radical reached the maximum when the cream was added to the cream of the golden chamomile extract with a mass concentration of 8.0 mg/mL.When adding 7% ring five polymethylsiloxane, 1.0% PEG - 60 and 13.3% glycerol with a mass fraction of five, the cream had the best comprehensive effect.The heat resistance, cold resistance and safety of the cream are in line with the cosmetic standard and have good antioxidant properties.Therefore, the compound anti - photoaging cream has good development and utilization value.
Keywords:chrysanthellum indicumchrysanthellum indicum  shea butter  face cream  antioxidant
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