| 一种MEMS结肠癌细胞捕获芯片研究 |
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| 引用本文： | 胡锐军,陈迪,陈翔,陈景东,吴澄,杜航向,杨治力,王志刚,夏骏.一种MEMS结肠癌细胞捕获芯片研究[J].功能材料与器件学报,2011,17(2):227-232. |
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| 作者姓名： | 胡锐军 陈迪 陈翔 陈景东 吴澄 杜航向 杨治力 王志刚 夏骏 |
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| 作者单位： | 微米纳米加工技术国家级重点实验室薄膜与微细技术教育部重点实验室上海交通大学微纳科学技术研究院;上海市第六人民医院;上海市第一人民医院; |
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| 基金项目： | 973项目(2010CB933901); 国家自然科学基金(20905047); 上海交通大学医工交叉基金(YG2009MS27) |
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| 摘 要： | 癌症是影响人类健康的重大疾病之一,如何快速、方便地分离癌细胞已经成为制约临床医学和科学研究的重要问题.本文将磁珠技术与MEMS技术相结合,提出了一种等边三角排列的Ni微磁柱结构,在磁场作用下使用CD326免疫磁珠捕获结肠癌细胞.本文对MEMS细胞捕获芯片进行了设计、加工和封装,采用该芯片对与磁珠结合的结肠癌细胞进行了捕...
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| 关 键 词： | 结肠癌细胞捕获 免疫磁珠 |
Study on MEMS Colon Cancer Cell Capturing Chip |
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| HU Rui-jun,CHEN Di,CHEN Xiang,CHEN Jing-dong,WU Cheng,DU Hang-xiang,YANG Zhi-li,WANG Zhi-gang,XIA Jun.Study on MEMS Colon Cancer Cell Capturing Chip[J].Journal of Functional Materials and Devices,2011,17(2):227-232. |
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| Authors: | HU Rui-jun CHEN Di CHEN Xiang CHEN Jing-dong WU Cheng DU Hang-xiang YANG Zhi-li WANG Zhi-gang XIA Jun |
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| Affiliation: | HU Rui-jun1,CHEN Di1,CHEN Xiang1,CHEN Jing-dong1,WU Cheng1,DU Hang-xiang2,YANG Zhi-li,WANG Zhi-gang2,XIA Jun3(1.National Key Laboratory of Nano/Micro Fabrication Technology,Key Laboratory for Thin Film and Microfabrication Technology of Ministry of Education,Research Institute of Micro/Nano Science and Technology,Shanghai 200240,China,2.Shanghai No.6 People's Hospital,Shanghai 200233,3.Shanghai No.1 People's Hospital,Shanghai 200080,China) |
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| Abstract: | Cancer is one of the major diseases threatening human health.It is a thorny problem to isolate cancer cells fast and easily for clinical medical officers and scientific researchers.Combining magnetic bead technology and MEMS technology,Ni micro-magnetic cylinder arranged in an equilateral triangle is designed to capture colon cancer cells using CD326 immune magnetic beads in magnetic field.In this paper,MEMS cell capturing chip was designed,micro-fabricated,and packaged.Colon cancer cells combined with magn... |
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| Keywords: | colon cancer cell capturing immunomagnetic beads |
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