In vitro degradation behaviors of Poly-<Emphasis Type="SmallCaps">l</Emphasis>-lactide/bioactive glass composite materials in phosphate-buffered solution |
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Authors: | Zhihua Zhou Qingfeng Yi Xiaoping Liu Lihua Liu Qingquan Liu |
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Affiliation: | (1) School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, People’s Republic of China;(2) State Key Laboratory for Powder Metallurgy, Central-South University, Changsha, People’s Republic of China |
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Abstract: | In vitro degradation behaviors of composite materials composed of poly-l-lactide (PLLA) and bioactive glass (BG) were systematically investigated up to 20 weeks in phosphate-buffered solution (PBS)
at 37 °C. The properties of PLLA/BG composites and PLLA materials, including weight loss, bending strength and modulus, shearing
strength, polymer molecular weight and its distribution, and the morphologies, were investigated as a function of degradation
time. The change of the pH value of the PBS media was also detected. The results showed that the presence of the bioactive
glass modified the degradation of the matrix polymer. The degradation rate of the PLLA/BG composites was slower than the degradation
rate of the sole PLLA materials. |
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