| 一种新型仿生骨组织工程支架的制备与表征 |
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| 引用本文： | 李向军,陈晓峰,王迎军,赵娜如,杨春蓉. 一种新型仿生骨组织工程支架的制备与表征[J]. 功能材料, 2007, 38(2): 295-297 |
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| 作者姓名： | 李向军 陈晓峰 王迎军 赵娜如 杨春蓉 |
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| 作者单位： | 华南理工大学,材料学院生物材料研究所,广东,广州,510640;华南理工大学,材料学院生物材料研究所,广东,广州,510640;华南理工大学,特种功能材料教育部重点实验室,广东,广州,510640 |
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| 基金项目： | 国家自然科学基金 , 广东省自然科学基金 , 国家重点基础研究发展计划(973计划) , 广东省广州市科技计划 |
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| 摘 要： | 利用改性生物玻璃粉体和胶原、透明质酸钠、磷酸丝氨酸等天然生物分子复合制备仿生型三维多孔骨组织工程支架材料,利用体外模拟实验结合SEM、FTIR、XRD 等测试方法对材料的显微结构、生物矿化性能进行了综合研究,研究表明该材料具有良好的孔隙结构,在模拟生理溶液(SBF)中反应24h即可在支架表面形成碳酸羟基磷灰石(HCA).
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| 关 键 词： | 仿生 多孔支架 生物矿化 |
| 文章编号： | 1001-9731(2007)02-0295-03 |
| 修稿时间： | 2006-07-28 |
Preparation and characterizaton of novel biomimetic composite scaffolds for bone tissue engineering applications |
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| LI Xiang-jun,CHEN Xiao-feng,WANG Yin-jun,ZHAO La-ru,YANG Chun-rong. Preparation and characterizaton of novel biomimetic composite scaffolds for bone tissue engineering applications[J]. Journal of Functional Materials, 2007, 38(2): 295-297 |
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| Authors: | LI Xiang-jun CHEN Xiao-feng WANG Yin-jun ZHAO La-ru YANG Chun-rong |
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| Affiliation: | 1. Biomaterials Research Institute, College of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China; 2. Key Laboratory of Specially Functional Materials of Ministry of Education, South China University of Technology, Guangzhou 510640,China |
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| Abstract: | The novel biomemetic composite scaffolds with similar components to natural bone using surface modified bioglass(SBG),collagen(COL),hyaluronic acid(HYA),and phosphoserine(PS) was prepared.The microstructure and bio-mineralization were synthetically analyzed in vitro using SEM,FTIR and XRD techniques.It was indicated that the scaffold possessed good porous structure,and hydroxy-carbonate-apatite crystals with a low crystallinity could formed on the surface of the scaffold immersed in SBF for 24h. |
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| Keywords: | biomimetic porous scaffold biomineralization |
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