Maximum Entropy Method in Analysis of Genetic Text and Measurement of its Information Content |
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| Authors: | N. N. Bugaenko A. N. Gorban M. G. Sadovsky |
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| Affiliation: | (1) Siberian Division of Russian Academy of Sciences, Computing Center, Akademgorodok, Krasnoyarsk, 660036;(2) Siberian Division of Russian Academy of Sciences, Institute of Biophysics, Akademgorodok, Krasnoyarsk, 660036 |
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| Abstract: | The information capacity in frequency dictionaries of nucleotide sequences is estimated through the efficiency of reconstruction of a longer frequency dictionary from a short one. This reconstruction is performed by the maximum entropy method. Real nucleotide sequences are compared to random ones (with the same composition of nucleotides). Phages genes from NCBI bank were analyzed. The reliable difference of real genetic texts from random sequences is observed for the dictionary length q = 2, 5 and 6. |
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