Adsorption of lipopolysaccharide on carbon sieves |
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Authors: | V.M. Gun&rsquo ko,S. Patel,S.V. Mikhalovsky |
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Affiliation: | a Institute of Surface Chemistry, 17 General Naumov Street, 03164 Kiev, Ukraine b Supelco Inc., Supelco Park, Bellefonte, PA 16823-0048, USA c School of Pharmacy and Biomolecular Sciences, University of Brighton, Cockcroft Building, Lewes Road, Brighton BN2 4GJ, United Kingdom |
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Abstract: | Adsorption of lipopolysaccharide, LPS, on carbon sieves Carboxen 1003 and Carboxen 1010 has been studied. LPS adsorption kinetics is initially faster on smaller size (1-10 μm) particles of predominantly microporous Carboxen 1010 compared to Carboxen 1003 (150-200 μm) particles. However, the adsorption capacity of micro/meso/macroporous Carboxen 1003 by LPS is higher than that of Carboxen 1010 since the former carbon has wider pores that can accommodate large lipopolysaccharide molecules or their agglomerates. Carboxen 1010 probably adsorbs LPS mainly on the external (macropore) surface. |
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Keywords: | Activated carbon Adsorption Microporosity Surface properties |
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