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Absence of Mal/TIRAP Results in Abrogated Imidazoquinolinones-Dependent Activation of IRF7 and Suppressed IFNβ and IFN-I Activated Gene Production |
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| Authors: | Ewa Leszczy&#x;ska Edyta Makuch Ma&#x;gorzata Mitkiewicz Izabella Jasyk Miwako Narita Sabina Grska Tomasz Lipi&#x;ski Jakub Siednienko |
| Affiliation: | 1.Bioengineering Research Group, Łukasiewicz Research Network–PORT Polish Center for Technology Development, 54-066 Wroclaw, Poland; (E.L.); (I.J.); (T.L.);2.Laboratory of Microbiome Immunobiology, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland; (E.M.); (M.M.); (S.G.);3.Laboratory of Hematology and Oncology, Niigata University, Niigata 950-2181, Japan; |
| Abstract: | |
| Keywords: | R848 R837 Toll-like receptor-7 Mal IRF7 Interferon-beta IP-10 |