Evaluation of natural Psoroptes ovis (Acarina: Psoroptidae) soluble proteins as candidate vaccine immunogens |
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Authors: | JH Pruett KB Temeyer WF Fisher PK Beetham SE Kunz |
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Affiliation: | Knipling-Bushland U.S. Livestock Insects Research Laboratory, USDA-ARS, Kerrville, TX 78028-9184, USA. |
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Abstract: | In this study potential vaccine candidate immunogens were identified and evaluated in a vaccine challenge trial. Calves vaccinated with a partially purified fraction of Psoroptes ovis-soluble proteins had 8 of 14 calves free of palpable lesions 8 wk after a challenge infestation. A self-grooming behavioral response elicited by a pruritic immediate-type allergic reaction was believed to be an effector in protecting the vaccinated calves from a clinical P. ovis infestation. |
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