Life stress and lymphocyte alterations among patients with rheumatoid arthritis. |
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Authors: | Zautra, Alex J. Okun, Morris A. Robinson, Sharon E. Lee, Douglas Roth, Sanford H. Emmanual, Jansen |
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Abstract: | Studied the relation between life stress and immune parameters for 33 30–70 yr old female rheumatoid arthritis (RA) patients interviewed during 3 routine monthly clinic checkups. Life stress from major and minor events, coping efficacy, and self-reported psychological distress were assessed, and immunofluorescence of T-cells and B-cells was performed on the blood drawn during each visit. Small stressful events were positively related to the proportion of circulating B-cells, psychological distress was inversely related to proportion of circulating T-cells, and major life events were associated with lower T-helper/T-suppressor cell ratios. (PsycINFO Database Record (c) 2010 APA, all rights reserved) |
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