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液相色谱-质谱联用技术在中药农药残留分析中的应用进展
引用本文:陈丽娜,宋凤瑞,刘志强. 液相色谱-质谱联用技术在中药农药残留分析中的应用进展[J]. 质谱学报, 2010, 31(6): 342-353
作者姓名:陈丽娜  宋凤瑞  刘志强
作者单位:1. 中国科学院长春应用化学研究所,长春质谱中心,吉林 长春130022;2.中国科学院研究生院,北京100049
基金项目:国家科技部科技支撑计划项目,国家科技部创新方法研究专项
摘    要:液相色谱-质谱联用(LC-MS/MS)技术在农药残留分析领域的研究已经显示出极大的发展潜力。本文阐述LC-MS/MS法在农残分析中的研究进展,特别强调了该技术在中药农残分析中的应用现状和发展前景。由于样品前处理是农残分析中耗时最多、最易引起误差的关键环节,本文也讨论了最近发展和广泛应用的前处理技术,分析了不同方法的特点,从而为我国中药行业在农药残留方面的监测工作提供参考。

关 键 词:中药材  农药残留  液相色谱-质谱联用(LC-MS/MS)  前处理  

Advances on Traditional Chinese Medicine Application of Liquid Chromatography-Tandem Mass Spectrometry and Correspondingly Sample Preparations in Pesticide Residue Analysis
CHEN Li-na,SONG Feng-rui,LIU Zhi-qiang. Advances on Traditional Chinese Medicine Application of Liquid Chromatography-Tandem Mass Spectrometry and Correspondingly Sample Preparations in Pesticide Residue Analysis[J]. Journal of Chinese Mass Spectrometry Society, 2010, 31(6): 342-353
Authors:CHEN Li-na  SONG Feng-rui  LIU Zhi-qiang
Affiliation:1. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; 2. Graduate School of Chinese Academy of Sciences, Beijing 100049, China
Abstract:The past few years show the considerable potential in the application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) to control pesticide residues for insure environment and food safety. This review focuses on the advances of LC-MS/MS analysis of pesticide residues and especially addressed its applications and prospect in the traditional Chinese medicine (TCM). Some sample preparation techniques which recently developed and extensively used are also surveyed as they are still mandatory in many applications for the reason of time consuming and easily errors. Furthermore, emphasis is placed on the advantages and disadvantages of them in order to provide information for pesticide residue control in Chinese medicine production.
Keywords:Chineseherbalmedicine  pesticideresidues  liquidchromatography-tandemmassspectrometry(LC-MS/MS);preparation  
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