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Hippocampectomy disrupts the topography of conditioned nictitating membrane responses during reversal learning.
Authors:Orr  William B; Berger  Theodore W
Abstract:The effects of bilateral hippocampectomy on the topography of conditioned nictitating membrane (NM) responses in 24 male New Zealand white rabbits were examined during 4 learning tasks: 1-tone delay conditioning, unpaired extinction, 2-tone discrimination, and reversal of 2-tone discrimination. Results show that hippocampal ablation altered conditioned NM response topography only during reversal learning and not during the other training paradigms. The shapes of learning curves for hippocampectomized Ss were different from those of controls only during reversal conditioning. Implications for unit-recording studies of hippocampal cellular activity during classical conditioning of the NM response are discussed. (21 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)
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