| 噻丙腈的合成与生物活性 |
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| 引用本文： | 刘红翼,褚岩凤,杨辉斌,于海波,梁博,宋玉泉,李斌. 噻丙腈的合成与生物活性[J]. 精细与专用化学品, 2012, 20(1): 45-47 |
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| 作者姓名： | 刘红翼 褚岩凤 杨辉斌 于海波 梁博 宋玉泉 李斌 |
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| 作者单位： | 1. 沈阳化工大学,辽宁沈阳110142／新农药创制与开发国家重点实验室（沈阳化工研究院有限公司）,辽宁沈阳110021
2. 新农药创制与开发国家重点实验室（沈阳化工研究院有限公司）,辽宁沈阳,110021 |
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| 基金项目： | 国家“十二五”科技支撑计划项目（2011BAE06B01）; 国家重点基础研究发展计划（973计划）项目（2010CB735601） |
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| 摘 要： | 噻丙腈是德国Schering公司于20世纪80年代开发的丙烯腈类杀虫剂,可用于防治马铃薯甲虫、梨木虱、菜蛾等害虫,具有结构新颖、高效、对作物安全、对蜜蜂及鱼类低毒等特点,是一种具有发展潜力的杀虫剂。介绍了噻丙腈的合成,对其进行了生物活性测定。并经核磁验证其结构。室内生物活性结果表明,该化合物对鳞翅目幼虫及蚜虫有优异的杀虫活性,同时发现其对朱砂叶螨也具有一定的活性。
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| 关 键 词： | 噻丙腈 杀虫剂 杀虫活性 |
Synthesis and bioactivity of thiapronil |
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| LIU Hong-yi,CHU Yan-feng,YANG Hui-bin,YU Hai-bo,LIANG Bo,SONG Yu-quan,.LI Bin. Synthesis and bioactivity of thiapronil[J]. Fine and Specialty Chemicals, 2012, 20(1): 45-47 |
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| Authors: | LIU Hong-yi CHU Yan-feng YANG Hui-bin YU Hai-bo LIANG Bo SONG Yu-quan .LI Bin |
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| Affiliation: | 1.Shenyang University of Chemical Technology,Shenyang 110042,China; 2.State Key Laboratory of the Discovery and Development of Novel Pesticide, (Shenyang Research Institute of Chemical Industry Co.,Ltd.,Shenyang 110021,China) |
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| Abstract: | Thiapronil was acrylonitrile insecticide which was developed by Germany Schering in the 1980s.It can be used to control potato beetles,pear psylla,moth and other pests.Thiapronil is a potential pesticide with relatively new structure,high efficiency,crop safety,low toxicity to bees and fish,etc.In this paper thiapronil was synthesized and its structure was confirmed by ~1HNMR.The results of biological activities evaluated in the greenhouse indicated that thiapronil has good activity against lepidoptera larvae and myzus persicae.Some activities against tetranychus cinnabarinus were also discovered. |
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| Keywords: | thiapronil insecticide insecticidal activity |
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