Solubility of β-cyclodextrin in different mixed solvents

The solubility of β-cyclodextrin(β-CD)in ionic liquid/N,N-dimethyl-acetamide(IL/DMAC)mixed solvent and in LiCl/DMAC mixed solvent was investigated at 323.15 K and 353.15 K.The results showed that the solubility of β-CD in IL/DMAC system increased with increasing temperature,but decreased in LiCl/DMAC system.β-CD had the highest solubility in IL/DMAC system with[Cl]- or[Br]- anions.The solubility of β-CD in LiCl/DMAC system was lower than that in IL/DMAC system with [Cl]- or[Br]- anions but higher than that in IL/DMAC system with weak-coordinated anions(e.g[BF4]- or[PF6]-).The effects of substituent groups(benzyl and butyl)of cation and the structure of cations on β-cyclodextrin solubility were also investigated.