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Functional Peptide Monolayers at Interfaces |
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| Authors: | Avigail Baruch Leshem Shlomo Zarzhitsky Hanna Rapaport |
| Affiliation: | 1. Unit of Environmental Engineering, Ben Gurion University of the Negev, Beer Sheva 8410 (Israel);2. Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 8410 (Israel) Department of Biotechnology Engineering, Ben Gurion University of the Negev, Beer Sheva 8410 (Israel);3. Ilse Katz Institute for Nanoscale Science and Technology, Ben Gurion University of the Negev, Beer Sheva 8410 (Israel) |
| Abstract: | Amphiphilic peptides can be designed to form ordered supramolecular structures at hydrophilic-hydrophobic interfaces. These systems rely on the ability of peptides to fold into certain secondary structures at interfaces. This review focuses on the design of amphiphilic β-sheet peptide assemblies in monolayers at interfaces, and their relevance to inducing mineralization and interactions with specific ions. In addition, the review discusses recent studies demonstrating the applicability of designed amphiphilic β-sheet peptides to detection of specific small molecules and to elucidating intermolecular interactions relevant to drug delivery and enzyme catalysis systems. |
| Keywords: | amphiphiles β-sheet structures enzyme catalysis peptides self-assembly |