|
|||||
|
|
4D Biofabrication: 3D Cell Patterning Using Shape‐Changing Films |
|
| Authors: | Vladislav Stroganov Jitendra Pant Georgi Stoychev Andreas Janke Dieter Jehnichen Andreas Fery Hitesh Handa Leonid Ionov |
| Affiliation: | 1. College of Engineering, University of Georgia, Athens, GA, USA;2. College of Family and Consumer Sciences, University of Georgia, Athens, GA, USA;3. Leibniz‐Institut für Polymerforschung Dresden e.V., Dresden, Germany;4. Faculty of Engineering Science University of Bayreuth, Bayreuth, Germany |
| Abstract: | A novel approach for fabrication of 3D cellular structures using new thermosensitive shape‐changing polymer films with photolithographically patterned surface—4D biofabrication is reported. The surface of shape‐changing polymer films is patterned to selectively adsorb cells in specific regions. The 2D cell pattern is converted to the 3D cell structure after temperature‐induced folding of the polymer films. This approach has a great potential in the field of tissue engineering and bioscaffolds fabrication. |
| Keywords: | actuators folding hydrogels thermoresponsive polymers |