Hemostasis in acquired hemophilia--role of intracavitary instillation of EACA |
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| Authors: | S Sahu R Raipancholia FK Pardiwalla AV Pathare |
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| Affiliation: | Department of Dr J C Patel Hematology, KEM Hospital, Parel, Mumbai. |
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| Abstract: | An 82 year old man developed antibodies against coagulation factor VIII:C without any apparent cause. Bleeding from the soft tissue cavity could not be controlled by factor VIII:C concentrates, immunosuppression with steroids and intravenous immunoglobulin therapy in the standard dosages. However, a single injection of Epsilon Aminocaproic Acid (EACA) instilled into the cavity under aseptic precautions achieved lasting hemostasis with resultant wound healing. |
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