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Genotoxic potential of aqueous extracts of Artemisia verlotorum on the cell cycle of Allium cepa |
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| Authors: | Luccas Fernando Bittencourt De Souza Haywood Dail Laughinghouse IV Tamara Pastori Marília Tedesco Andrielle Wouters Kuhn Thais Scotti Do Canto‐Dorow |
| Affiliation: | 1. Curso de Agronomia , Universidade Federal de Santa Maria, UFSM , Santa Maria, RS, Brazil;2. Department of Environmental Science and Technology , University of Maryland , College Park, MD, USA;3. Department of Botany, National Museum of Natural History , Smithsonian Institution , Washington, DC, USA;4. Departamento de Biologia , Universidade Federal de Santa Maria, UFSM , Santa Maria, RS, Brazil |
| Abstract: | Artemisia verlotorum, popularly ‘infalivina’, is a medicinal herb used for respiratory, circulatory and digestive treatments. Antiproliferative and genotoxic effects of A. verlotorum aqueous extracts in three different concentrations (6, 32 and 48 g/L) were evaluated on the Allium cepa cell cycle. Results clearly showed a significant difference using the χ2 test (p = 0.05) among treatments with a decrease in the mitotic index as the concentration of the extract increased. Extracts of A. verlotorum proved to be genotoxic and showed antiproliferative potential on the A. cepa cell cycle. This study suggests the use of infusions of A. verloturum for medicinal purposes only after selecting suitable concentrations. |
| Keywords: | Medicinal plant Artemisia verlotorum Genotoxicity Chromosomal aberration Plant genetics resources |