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淋巴因子相应靶细胞的小剂量辐射效应
引用本文:刘伟宏,李修义.淋巴因子相应靶细胞的小剂量辐射效应[J].辐射研究与辐射工艺学报,1994,12(2):75-78,108.
作者姓名:刘伟宏  李修义
作者单位:白求恩医科大学放射生物教研室
摘    要:观察了单次小剂量X射线全身照射后C57BL/6小鼠胸腺细胞IL-1反应性和脾细胞IL-2反应性的变化,发现在100mGy以内的小剂量照射后,整个胸腺和脾脏的细胞数趋于增多,胸腺细胞对IL-1的反应性和脾细胞对IL-2的反应性趋于增强,体外照IL-2细胞亦出现同样的反应趋势,但统计学处理与对照组比较均地明显差异。

关 键 词:小剂量辐照  生物效应  淋巴细胞

EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED
Liu Weihong, Li Xiuyi, Liu Shuzheng.EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED[J].Journal of Radiation Research and Radiation Processing,1994,12(2):75-78,108.
Authors:Liu Weihong  Li Xiuyi  Liu Shuzheng
Abstract:The changes of reactivities of thymocyte to IL-1 and splenocyte to IL-2 were studied in C 57 BL/6 mice after whole body X-irradiation with low doses. It was found that the number of thymocyte and splenocyte was increased,the reactivities of thymocyte to IL-1 and splenocyte to IL-2 also showed a tendency to increase after X-irradiation with low doses below 100 mGy, but the increase was statisticaly not significant. There was a same effect of low dese radiation on the CTLL-2, growing dependent on IL-2, irradiated in vitro.
Keywords:Low dose radiation  Interleukin-1 (IL-1)  Interleukin-2 (IL-2)  CTLL-2 cell
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