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Strategic Targeting of Multiple Water‐Mediated Interactions: A Concise and Rational Structure‐Based Design Approach to Potent and Selective MMP‐13 Inhibitors |
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| Authors: | Thomas Fischer Prof. Dr. Rainer Riedl |
| Affiliation: | Institute for Chemistry and Biological Chemistry, Zurich University of Applied Sciences (ZHAW), Einsiedlerstrasse 31, 8820 W?denswil (Switzerland) www.icbc.zhaw.ch/organic‐chemistry |
| Abstract: | |
| Keywords: | chemical biology matrix metalloproteinase inhibitors structure‐based drug design structure– activity relationships water‐mediated interactions |