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Inside Cover: Monitoring Binding of HIV‐1 Capsid Assembly Inhibitors Using 19F Ligand‐and 15N Protein‐Based NMR and X‐ray Crystallography: Early Hit Validation of a Benzodiazepine Series (ChemMedChem 3/2013) |
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| Authors: | Dr Nathalie Goudreau René Coulombe Dr Anne‐Marie Faucher Chantal Grand‐Maître Jean‐Eric Lacoste Dr Christopher T Lemke Eric Malenfant Yves Bousquet Dr Lee Fader Dr Bruno Simoneau Jean‐François Mercier Steve Titolo Dr Stephen W Mason |
| Affiliation: | 1. Dept. of Chemistry and Biological Sciences, Research & Development, Boehringer Ingelheim (Canada) Ltd, 2100 Cunard Street, Laval, Québec, H7S 2G5 (Canada);2. Department of Chemistry, University of Montreal, C.P. 6128, succursale Centre‐ville, Montreal, Québec, H3C 3J7 (Canada);3. AL‐G Technologies Inc. 201 Mgr. Bourget, Lévis, Québec, G6V 9V6 (Canada);4. Virology, Bristol‐Myers Squibb, 5 Research Parkway, Wallingford, CT 06492 (USA) |
| Abstract: | |
| Keywords: | binding studies fluorine HIV‐1 capsids NMR spectroscopy X‐ray crystallography |