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(4R)‐ and (4S)‐Fluoroproline in the Conserved cis‐Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering |
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| Authors: | Dr. Marina Rubini Dr. Martin A. Schärer Dr. Guido Capitani Prof. Rudi Glockshuber |
| Affiliation: | 1. Department of Organic Chemistry/Cellular Chemistry, University of Konstanz, Universit?tsstrasse 10, 78464 Konstanz (Germany);2. Institute of Molecular Biology and Biophysics, ETH Zürich, Schafmattstrasse 20, 8093 Zürich (Switzerland);3. Laboratory ofBiomolecular Research, Paul Scherrer Institute, OFLC 110, 5232 Villigen (Switzerland) |
| Abstract: | |
| Keywords: | cis peptide bonds fluoroprolines proline ring puckers protein engineering protein structures |