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The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti‐Alzheimer Multitarget Profile of Dimebon |
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| Authors: | Dr. Michela Rosini Dr. Elena Simoni Dr. Manuela Bartolini Dr. Elena Soriano Prof. José Marco‐Contelles Prof. Vincenza Andrisano Dr. Barbara Monti Dr. Manfred Windisch Dr. Birgit Hutter‐Paier Dr. David W. McClymont Dr. Ian R. Mellor Prof. Maria Laura Bolognesi |
| Affiliation: | 1. Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126 Bologna (Italy);2. Instituto de Quimica Organica General (CSIC), Juan de la Cierva, 3, 28006 Madrid (Spain);3. Department for Life Quality Studies, Alma Mater Studiorum‐University of Bologna, Rimini Campus, Italy;4. JSW Lifesciences GmbH, Parkring 12, 8074 Grambach (Austria);5. School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD (UK) |
| Abstract: | |
| Keywords: | acetylcholinesterase Alzheimer’ s disease amyloid aggregation butyrylcholinesterase dual binding inhibitors NMDA receptors |