Binding of Bile Salts by Soluble Fibers and Its Effect on Deconjugation of Glycocholate by Lactobacillus acidophilus and Lactobacillus casei. |
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Authors: | EP Cuesta-Alonso SE Gilliland |
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Affiliation: | Authors are with the Dept. of Animal Science and Food and Agricultural Products Research and Technology Center, Oklahoma State Univ., Stillwater, OK 74078. Direct inquiries to author Gilliland (E-mail: ). |
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Abstract: | ABSTRACT: Binding of sodium cholate, sodium taurocholate, and sodium glycocholate by guar gum, soluble oat fiber, xanthan gum, and inulin was studied. All soluble fibers were able to bind sodium cholate, sodium taurocholate, and sodium glycocholate from a mixture of the three, but when tested individually, the fibers bound little or no sodium cholate. In general, the fibers bound higher concentrations of conjugated bile salts than they did free bile salts. Soluble oat fiber, which bound as much or more sodium cholate and sodium glycocholate as did the other 3 fibers, was tested for its effect on deconjugation of glycocholate by Lactobacillus acidophilus and Lactobacillus casei. The presence of the fiber significantly increased (P < 0.05) deconjugation by all cultures. |
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Keywords: | soluble fibers bile salts deconjugation Lactobacillus |
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