Transmission of Chlamydia trachomatis and Neisseria gonorrhoeae among men with urethritis and their female sex partners |
| |
Authors: | JS Lin SP Donegan TC Heeren M Greenberg EE Flaherty R Haivanis XH Su D Dean WJ Newhall JS Knapp SK Sarafian RJ Rice SA Morse PA Rice |
| |
Affiliation: | The Maxwell Finland Laboratory for Infectious Diseases, Boston, MA 02118-2393, USA, |
| |
Abstract: | Transmission of Chlamydia trachomatis and Neisseria gonorrhoeae among infected men and their female sex partners was examined using a design enhancing the likelihood that spread was directed from men to women. Chlamydia culture-negative specimens were examined using DNA amplification tests. Infection rates in women exposed to male sex partners with Chlamydia only were 65% (20/31) and with gonorrhea only were 73% (33/45). Infection of women by either agent was not influenced by the number of sexual exposures to or coinfection in men. There was a 98% (40/41) concordance of N. gonorrhoeae isolates among partners by auxotype and serovar. Chlamydia isolates were serotyped using ELISA and immunofluorescence testing and confirmed by nested polymerase chain reaction: 50% (6/12) of men and 57% (8/14) of women yielded mixed serovars. Sixty-four percent of pairs (9/14) were infected with identical serovars and an additional 28% shared at least one serovar. Multiple serovars of C. trachomatis, but not of N. gonorrhoeae, were common in sex partners and exchanged frequently. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|