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Discovery of a New Class of Liver Receptor Homolog‐1 (LRH‐1) Antagonists: Virtual Screening,Synthesis and Biological Evaluation
Authors:Dr. Jullien Rey  Dr. Haipeng Hu  Dr. Fiona Kyle  Chun‐Fui Lai  Dr. Laki Buluwela  Prof. R. Charles Coombes  Prof. Eric A. Ortlund  Prof. Simak Ali  Prof. James P. Snyder  Prof. Anthony G. M. Barrett
Affiliation:1. Department of Chemistry, Imperial College London, London, SW7 2AZ (England);2. Department of Chemistry and Emory Institute for Drug Development, Emory University, 1515 Dickey Drive, Atlanta, GA 30322 (USA);3. Department of Surgery and Cancer, Imperial College London, London, W12 0NN (England);4. Department of Biochemistry, Emory University, School of Medicine, 1510 Clifton Rd NE, Atlanta, GA 30322 (USA)
Abstract:
Keywords:antagonists  breast cancer  high‐throughput virtual screening  ligand binding domains  nuclear receptor
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