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A grid environment for high-throughput proteomics
Authors:Cannataro Mario  Barla Annalisa  Flor Roberto  Jurman Giuseppe  Merler Stefano  Paoli Silvano  Tradigo Giuseppe  Veltri Pierangelo  Furlanello Cesare
Affiliation:Univ. Magna Graecia, Catanzaro;
Abstract:We connect in a grid-enabled pipeline an ontology-based environment for proteomics spectra management with a machine learning platform for unbiased predictive analysis. We exploit two existing software platforms (MS-Analyzer and BioDCV), the emerging proteomics standards, and the middleware and computing resources of the EGEE Biomed VO grid infrastructure. In the setup, BioDCV is accessed by the MS-Analyzer workflow as a Web service, thus providing a complete grid environment for proteomics data analysis. Predictive classification studies on MALDI-TOF data based on this environment are presented.
Keywords:
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