Stimulatory effects of tannins and cholic acid on tryptic hydrolysis of proteins: Ecological implications |
| |
Authors: | Simon Mole Peter G Waterman |
| |
Affiliation: | (1) Phytochemistry Research Laboratories Department of Pharmacy (Pharmaceutical Chemistry), University of Strathclyde, G1 1XW Glasgow, Scotland |
| |
Abstract: | The biochemical basis for considering tannins as digestion inhibitors has been reexamined. Both stimulatory and inhibitory effects of tannins on tryptic hydrolysis are reported. We show how stimulation may result from tannin-induced structural changes in the substrate protein, effectively denaturing it. The surfactant and bile constituent cholic acid also produced similar stimulatory effects. These results have considerable implications for normal digestive physiology as well as for the impact of tannins on argicultural and natural herbivore populations. |
| |
Keywords: | Tannins digestion herbivory digestibility-reducing substances gut surfactants bile acids tannin-protein interactions |
本文献已被 SpringerLink 等数据库收录! |