一种新型离子交换树脂在扩张床中性能的研究

在扩张床中研究了以水或甘油水溶液为流动介质,新型离子交换树脂CG-6在不同流速、粘度和床层沉降高度条件下的扩张率及柱效能,并使用牛血清白蛋白进行了扩张床吸附穿透实验。结果表明CG-6树脂在扩张床条件下具有很好的柱效能,轴向混合系数可达到10-6数量级,并且树脂对牛血清白蛋白有很高的吸附量,并且在合适的条件下有较好穿透性能。说明CG-6树脂适合于蛋白质的扩张床吸附,所得结果将在CG-6树脂在蛋白质分离纯化的应用中提供重要的参考依据。

The Properties of a New Ion-exchange Resin in Expanded Bed

A new ion-exchange resin,CG-6 is Experimented in a expanded bed.The ratio of expanding and column efficiency is determined at different flow velocity,viscosity and sediment bed height using water or glycerol solution as the fluid medium.The break through curves of Bovine Serum Albumin in expanded bed are also described.CG-6 shows very great column efficiency,the magnitude of axial mixing coefficient can reach 10-6.CG-6 has very great adsorption capability and rather fine break through property in appropriate conditions.The results demonstrate that CG-6 is suitable for the adsorption of protein in expended bed.This article will provide important basis for the application of CG-6 in purification of protein.