Effect of reaction conditions on the catalytic performance of H3PW12O40 heteropolyacid catalyst in the direct preparation of dichloropropanol from glycerol in a liquid-phase batch reactor

Direct chlorination of glycerol to dichloropropanol (DCP) was conducted in a liquid-phase batch rector using homogeneous H₃PW₁₂O₄₀ heteropolyacid (HPA) catalyst. The effect of reaction conditions (reaction time, reaction pressure, reaction temperature, and catalyst amount) on the catalytic performance of H₃PW₁₂O₄₀ in the direct preparation of DCP from glycerol was examined. The optimum reaction pressure and reaction temperature were found to be 10 bar and 130 °C, respectively. The reaction temperature was more crucial than the reaction pressure in improving the selectivity to DCP. Selectivity to DCP increased with increasing reaction time and with increasing catalyst amount. Acid sites of H₃PW₁₂O₄₀ catalyst favorably devoted to the chlorination of glycerol. H₃PW₁₂O₄₀ served as an efficient catalyst in the direct preparation of DCP from glycerol under the mild reaction conditions.